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American Society of Microbiology ABMM Exam Syllabus Topics:

American Society of Microbiology ABMM Sample Questions:

Question 1

A patient with a prosthetic joint develops a chronic infection. Multiple synovial fluid cultures grow a Gram- positive coccus that forms a biofilm and is resistant to multiple antibiotics, including methicillin and gentamicin. The MOST likely organism is:

A. Enterococcus faecium
B. Streptococcus agalactiae
C. Staphylococcus aureus
D. Staphylococcus epidermidis

Question 2

A fungal isolate grown from a blood culture at 37°C shows budding yeast cells. When subcultured to cornmeal agar with Tween 80 and incubated at 25°C, it produces pseudohyphae and terminal chlamydospores.
Growth on CHROMagar Candida yields green colonies. This organism is most likely:

A. Candida glabrata
B. Candida parapsilosis
C. Cryptococcus neoformans
D. Candida albicans

Question 3

A clinical microbiology laboratory is performing antimicrobial susceptibility testing on a Streptococcus pneumoniae isolate using broth microdilution. The lowest concentration of antibiotic that inhibits visible growth of the organism is reported as the:

A. Minimum inhibitory concentration (MIC)
B. Breakpoint
C. Zone diameter
D. Minimum bactericidal concentration (MBC)

Question 4

A patient with HIV infection and a CD4+ T-cell count of 30 cells/µL develops progressive multifocal leukoencephalopathy (PML). The causative agent of PML is:

A. Human herpesvirus 6 (HHV-6)
B. Epstein-Barr virus (EBV)
C. Cytomegalovirus (CMV)
D. JC virus (JCV)

Question 5

Microscopic examination of a trichrome-stained stool smear reveals amoebic trophozoites approximately 25
µm in diameter, containing ingested red blood cells. The nucleus, when visible, has fine, evenly distributed peripheral chromatin and a small, central karyosome. These features are diagnostic for:

A. Entamoeba coli
B. Endolimax nana
C. Entamoeba histolytica
D. Iodamoeba bütschlii

Solutions: